Research reveals why redheads may have different pain thresholds

Humans and mice with red hair have a different tolerance for pain because their skin's pigment-producing cells lack the function of a certain receptor. Lack of this receptor function causes changes that tip the balance between pain sensitivity and pain tolerance. The findings may be helpful for designing new treatments for pain.

source https://www.sciencedaily.com/releases/2021/04/210403153628.htm