Structural biology provides long-sought solution to innate immunity puzzle

Researchers report the first structural confirmation that endogenous -- or self-made -- molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex. The work has wide-ranging implications for finding ways to treat and possibly prevent autoimmune diseases such as multiple sclerosis and antiphospholipid syndrome.

source https://www.sciencedaily.com/releases/2021/07/210722112920.htm