Cytokine APRIL protects from atherosclerotic cardiovascular disease

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques. Researchers have now identified that a cytokine called A Proliferation Inducing Ligand (APRIL) plays a major protective role against the formation of atherosclerotic plaques.

source https://www.sciencedaily.com/releases/2021/08/210826111704.htm