By 2500 Earth could be alien to humans

To fully grasp and plan for climate impacts under any scenario, researchers and policymakers must look well beyond the 2100 benchmark. Unless CO2 emissions drop significantly, global warming by 2500 will make the Amazon barren, the American Midwest tropical, and India too hot to live in, according to a team of international scientists.

source https://www.sciencedaily.com/releases/2021/10/211014131214.htm