It takes more than one mutant copy of the PIK3CA gene to make breast cancer more aggressive, study finds

Breast cancers that have an overactive PI3K enzyme tend to be more aggressive and to spread and divide more like stem cells. But a new study uncovers a surprising relationship between PI3K activity and mutations in the PIK3CA gene that codes for the enzyme.

source https://www.sciencedaily.com/releases/2021/11/211111154249.htm