Sulfolobus islandicus, an archaeal model organism, offers unique advantages for metabolic engineering and synthetic biology applications owing to its ability to thrive under low pH and high temperature conditions. Although several genetic tools exist for this organism, the absence of well-defined chromosomal integration sites continues to limit its development as a cellular factory.
source https://phys.org/news/2026-01-sulfolobus-islandicus-genetic-toolkit-drug.html
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