New clues why gold standard treatment for bipolar disorder doesn't work for majority of patients

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it. This leaves them at risk for debilitating, potentially life-threatening mood swings. Researchers have found that the culprit may lie in gene activity -- or lack of it.

source https://www.sciencedaily.com/releases/2021/01/210105095628.htm