Researchers discover gene linked to bone cancer in children, ID potential novel therapy

Researchers have discovered a gene, OTUD7A, that impacts the development of Ewing sarcoma, a bone cancer that occurs mainly in children. They have also identified a compound that shows potential to block OTUD7A protein activity. Critical relationships between proteins contribute to the development of cancers such as Ewing sarcoma. So, it was a seminal discovery when the researchers found that OTUD7A controls the cancer-causing fusion protein.

source https://www.sciencedaily.com/releases/2021/06/210601152008.htm